Uncertainty and fear linger on as the pandemic doesn’t seem to loosen its clench over the world in the coming weeks. Research has been going on for months now, but no antidote has been found yet. With more than 150 drugs being under research now, there happens to be bewilderment and apprehension among the public about the looming effects of the virus. Now, as the situation is getting slightly better, the people have become ignorant of the fact that the world is still in the dark phase. More awareness needs to go into the communities that are less concerned about the issues out there. While the treatment for the virus is still under question, several answers have now started germinating, which may or may not be the conclusion to the pandemic.
The most promising treatments are being assessed through the Solidarity trial that was launched by the World Health Organization. Dexamethasone is a medicine that the UK has been trying on their patients, and it seems to be saving the lives of many of the seriously ill ones. According to the United Kingdom, their Recover trail is the world’s biggest trials with over 11,000 patients taking part in it. Survivors’ blood is also being tested upon for any possible cure that can help the ones who have been badly affected.
While many such pieces of research are going into forming the big picture of the Solidarity trial, there happen to be only three prevalent broad approaches of investigation. The first one is the antiviral drugs that can attack the coronavirus to hamper on its ability to thrive. As the patients’ immune system is being affected by the virus, it overreacts when any form of illness hits them, and the condition aggravates. Secondly, the world of research is focussing on drugs that calm the immune system of the patients so that they don’t fall into a state of collateral damage in their body. The third major approach is that of the antibodies that attack the virus, and these could be either made in a lab or extracted from the survivors’ blood.
Although no drug seems to have an adequate effect in pushing the virus out of one’s body completely, many of the trials prove that the drugs stand a chance against the sprawling virus. Dexamethasone is one of the first drugs to have shown the capability to save lives of people. The risk of death was cut by a fifth for the patients on oxygen and a third for those on ventilators by taking dexamethasone. Remdesivir, which is an antiviral drug that was developed to treat Ebola, showed some positive results initially in the clinical trials. By using it, the duration of symptoms was cut down from 15 to 11 days. It has proven to aid recovery but not in the prevention of death from coronavirus. Antivirals have, therefore, been considered as effective in the early stages, and the immune drugs to be used in the later stages. The UK has been using both remdesivir and dexamethasone to fight the pandemic.